Orthodox MS symptoms treatment
Orthodox medicine presently is using two drugs groups to possibly reduce MS symptoms:
- corticosteroids (prednisone, methylprednisone, ...)
- multiple sclerosis immunemodulatory drugs
Orthodox medicine, driven by very powerful multi-billion pharmaceutical industry, proposes some medicines for some multiple sclerosis symptoms treatment. Today's reality - every drug available in medicine today carries a risk of side effects, including over the counter remedies.
No corticosteroid treatment is currently approved, however, those disease modifying therapies that reduce progression of Primary Progressive and Progressive/Relapsing Multiple Sclerosis MS may be beneficial.
Currently used multiple sclerosis drugs are immunomodulatory. This means the approved drugs used specifically in the treatment of multiple sclerosis have a direct effect on immune system and therefore their use carries the risk of compromising the body' s ability to fight infection and may also interfere with the body' s tumor surveillance mechanisms...
The main problem is - the mechanisms by which the drugs exert their influence on the course of multiple sclerosis exacerbations is unknown. By definition this makes them experimental.
There are lots of information about all approved for MS treatment drugs. However, possible (and existing) side effects (sometimes very dangerous) are not so well documented.
Corticosteroids
Corticosteroids are prescribed for literally hundreds of conditions, including multiple sclerosis.
Short-term treatment (3-5 days) with corticosteroids (like prednisone, methylprednisolone, dexamethasone, others) can aid during periods of acute relapse.
Corticosteroids work by possibly decreasing the intensity of the body's defense system's reaction to the myelin in the central nervous system.
Many of the side–effects of steroids are predictable. Not all side–effects occur in all patients. All are related to:
- the amount of steroid a patient takes a day
- the length of time the patient remains on the medication
Prednisone is a replacement for a naturally in a body synthetised steroid Hydrocortisone, which was replaced with Prednisone because of the only reason - it can not be patented! So presently instead of natural steroid hormone is used synthetic one, containing lots of danfgerous adverse effects. More about many healing aspects of Hydrocortisone and other natural hormones - in an article 'Hormones and Chronic Disease', where David Brownstein, MD, states: "I have yet to see a patient with rheumatoid arthritis or scleroderma (or other autoimmune disorders) who has normal hormone levels".
Benefits
- To hasten recovery from acute attacks
- To prevent damage to the blood-brain barrier.
Some reported side effects:
- Sodium retention
- Increased appetite
- Increased fat deposits
- Increased acid in your stomach
- Increased sweating, especially at night
- Increased hair growth
- Acne on the face, back, and chest
- Bone and muscle problems
- Growth problems in children
- Eye problems
- Increased sugar in the blood
- Increased sensitivity to the sun
- Delayed wound healing
- Decreased ability to fight infection
- Thrush (Candida) growth in the mouth...
By the way, very interesting and truthful explanation how steroids are worsening the situation came from web site "Electroherbalism" chapter "Autoimmune Disorders":
The normal prescription for inflammatory disorders are strong antiinflammatories like steroids. These can certainly decrease symptoms but since they are covering up the problem and doing nothing to treat it, make it worse in the long run. A more ridiculous prescription for treating a pathogen-induced illness is a drug which decreases immune function. Since there are less immune cells to "call to arms" there is less inflammation. I can think of no better way to allow a pathogen to overrun and destroy tissue more quickly.
I initially was treated with mega dozes of injectable methyl-prednisone (Solu Medrol) and my situation after such a treatment worsened significantly.
MS immunomodulatory drugs
Avonex
Interferon beta-1a, recombinant DNA produced synthetic of naturally occurring proteins.
Benefits
- To lower incidence of disease resistance associated with this dosing regimen
Some reported side effects:
- Anaphylaxis
- Autoimmune Disorders
- Depression and Suicide
- Hepatic Injury and Hepatitis
- Injection Site Necrosis ...
Unknowns:
- Safety and Efficacy
- Drug Interactions
- Carcinogenesis
- Pregnancy and Fertility...
Betaseron (Betaferon)
Interferon beta-1b is a recombinant DNA produced synthetic of naturally occurring proteins. It is manufactured by bacterial fermentation.
Benefits
- To decrease rate of relapse
- To decrease development of new lesions
- To delay progression of disability
Some reported side effects:
- Adverse Events
- Anaphylaxis
- Autoimmune Disorders
- Depression and Suicide
- Hepatic Injury and Hepatitis
- Psychiatric Disorders
- Seizures
- Thyroid...
Unknowns:
- Safety and Efficacy
- Drug Interactions
- Carcinogenesis
- Spontaneous Abortion...
Copaxone
Glatiramer acetate (formerly copolymer-1)
Benefits
- To decrease rate of relapse
- To moderately decrease development of new lesions
- To probably delay progression of disability
Some reported side effects:
- Adverse Events
- Anaphylaxis
- Autoimmune Disorders
- Chest Pains
- Depression and Suicide
- Hepatic Injury and Hepatitis...
Unknowns:
- Safety and Efficacy
- Carcinogenesis
- Drug Interactions
- Impairment of Fertility...
Rebif
Interferon beta-1a - recombinant DNA produced synthetic of naturally occurring proteins.
Benefits
- To decrease rate of relapse
- To decrease development of new lesions
- To delay progression of disability
Some reported side effects:
- Anaphylaxis
- Autoimmune Disorders
- Depression and Suicide
- Flu-like Symptoms
- Hepatic Injury and Hepatitis
- Pregnancy...
Unknowns:
- Safety and Efficacy
- Drug Interactions
- Carcinogenesis
- Impairment of Fertility
- Nursing Mothers...
We know that all drugs used to treat multiple sclerosis
- are mainly experimental
- induce dangerous side effects
- are associated with dangerous uknowns
That means that every multiple sclerosis sufferer before treatment must balance carefully MS symptoms reduction against the potential for adverse side effects.
Final notes:
- I have no personal experience with multiple sclerosis drugs. I think I am extremely lucky (I wasn't treated with any of them), especially considering that I know MS sufferers who had to discontinue such a treatment because of terrible and dangerous adverse effects.
- I am not interested in multiple sclerosis drugs at all. However, substantially more complete, well presented and documented information can be found in a website specifically designed for multiple sclerosis drugs.
- My most important message to all MS-ers - multiple sclerosis can be cured or at least tempered with all-natural dietary supplements
Comments
Dear sir,
Thank u 4 tese informations , i'm 1 of ms patients, i want to ask which 1 of the above drugs is more benifits to ms , & is there any new researchs on new ms drugs .
Thank u again.
What a crock of sh!t !! I have ms, SPMS and nothing I have tried over the years has done anything, and believe me I have tried everything. I am too tired to list what I have done over the years. I am now basically bed ridden, extremly stiff, no balance and in incredible amounts of pain. If what you said really helps heal ms I would be healed of ms. It is a total crock and you should be ashamed of yourself.
I was diagnosed with MS August of 1995. Did not follow up on medication 'till maybe mid of 2001. From that time I have been on and of medication because either I had to change it to something more tolerable, or I was out of work (and insurance coverage). Last time was close to a year off Copaxone and had a new health insurance that approved a new MRI for me. My doctor could not believe that the brain liaisons were gone from the last MRI while on Copaxone. an exam at my eye-doctor also indentified right eye had .025 decreased astigmatism reading from the previous reading. I am now reluctantly taking Avonex. Feel much-much better than when I was on Copaxone though, but I really want to get a "natural" remedy. I do take a list of vitamins and minerals daily, my diet is not always spot-on, but I try. Enzymes was my next thing to try for mom (for lung condition) but I found her not in a position to experiment, so I will start it on me first... You will be hearing from me soon!
I was diagnosed in 2001 .. have taken 2 different therapies, Avonex when I was first diagnosed and spent about 18 months "getting use to" the side effects before I just couldn't take being sick for 6 out of 7 days and taking the shot again the night of the 7th day.. and Copaxone that was some real crap for my body .. started taking it in October and then by December (when I quit using it) I was having such bad joint and muscle pain I had to go to the doctor just to get pain meds and muscle relaxers .. BTW it's still very bad still taking all the pills that I started taking in December and taking more of them some days... have gone back to just taking my medicine cabinet full of vitamins that seem to work at keeping my MS monster at bay ... may taste like crap and have to drink about a gallon of water to get them down but it works better and BIGGEST PLUS I don't have to use a NEEDLE for them
my doctor told me to never take anything to boost my ammune system because that is what attacks the nerves. any reply?
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